Sebastien successfully completed porting GnomeMeeting to Avahi. Therefore I declare him the first one to port a "real world" application to Avahi. Hurrah! Screenshot here.
Shortly after, Sebestien - not lazy - announced his new Zeroconf service browser applet based on Avahi. It contains a drop down menu with all Zeroconf services found on your LAN. If you select a menu item the applet will execute the application that has been defined as Gnome URL handler for the specific protocol.